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Sclerosi multipla Newsletter by Xagena

ALERT Sclerosi multipla !

Effetti della Cannabis sulle capacità cognitive nei pazienti con sclerosi multipla

Sono stati determinati i correlati funzionali e strutturali di neuroimaging di disfunzioni cognitive associate con l’uso di Cannabis nella sclerosi multipla. In uno studio trasversale, 20 soggetti …

Daclizumab HYP superiore ad Avonex nel ridurre la frequenza annualizzata delle ricadute in pazienti con sclerosi multipla recidivante-remittente

I risultati completi dello studio di fase 3 DECIDE hanno mostrato un miglioramento statisticamente significativo nel ridurre l’attività della malattia nei pazienti con sclerosi multipla recidivante-r …

MediExplorer :: Bancadati di notizie tratte dalla letteratura medico-scientifica

Alfacalcidolo migliora il senso di stanchezza nei pazienti con sclerosi multipla

Un analogo sintetico della Vitamina-D, Alfacalcidolo ( anche noto come 1a-idrossivitamina D3; Dediol ) riduce il senso di stanchezza nei pazienti con sclerosi multipla. Inoltre, l’Alfacalcidolo ha anche migliorato la qualità di vita e ha ridotto … Leggi

Accumulo di ferro nella materia grigia profonda: associazione con il deterioramento cognitivo nella sclerosi multipla

C’è una correlazione ben stabilita tra l’atrofia della materia grigia profonda e la disfunzione cognitiva nella sclerosi multipla. Tuttavia, la causa di questi segni di neurodegenerazione è poco conosciuta. L’accumulo di ferro nella … Leggi

Il trattamento con Fingolimod porta a un aumento del volume maculare nella sclerosi multipla

Uno studio osservazionale ha cercato di determinare se Fingolimod ( Gilenya ), un modulatore del recettore della sfingosina-1-fosfato per via orale approvato per il trattamento della sclerosi multipla, porta generalmente a un aumento del volume del … Leggi

Neurology Updates

Atrial fibrillation: left atrial appendage occlusion is noninferior to Warfarin for ischemic stroke prevention or systemic embolism more than 7 days postrandomization

In the PROTECT AF ( Watchman Left Atrial Appendage Closure Technology for Embolic Protection in Patients With Atrial Fibrillation ) trial that evaluated patients with nonvalvular atrial fibrillation ( …

Patent foramen ovale closure with Amplatzer appears superior to medical therapy in preventing strokes in patients with cryptogenic embolism

Up to 40% of ischaemic strokes are cryptogenic. A strong association between cryptogenic stroke and the prevalence of patent foramen ovale ( PFO ) suggests paradoxical embolism via PFO as a potential …

Stroke prevention: community screening for atrial fibrillation using iPhone ECG in pharmacies

Atrial fibrillation causes a third of all strokes, but often goes undetected before stroke. Identification of unknown atrial fibrillation in the community and subsequent anti-thrombotic treatment coul …

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Alpha-synuclein

Higher levels of alpha-synuclein reverse symptoms in Parkinson …
benefits in ON-time, OFF-time …

Further long-term Safinamide use in these … in motor function …
Cholinesterase inhibitors

Efficacy and adverse effects of cholinesterase inhibitors and …
Acetylsalicylic acid

A randomized trial showed that Aspirin ( Acetylsalicylic acid ) is …
Aubagio

Teriflunomide ( Aubagio ) is a once-daily oral immunomodulator …
Copaxone

Search results for “Copaxone” … Sclerosis, provided evidence …
No clinical benefit of …

The proportion of patients with a … no clinical benefit of …
Dimethyl fumarate

Tecfidera for the treatment of adult patients with relapsing remitting …
Safinamide as add-on to …

Safinamide as add-on to Levodopa in mid to late …
Cocaine

Cocaine addiction: molecular … Cocaine might increase their …

Multiple Sclerosis Updates

Multiple Sclerosis News

Relapsing-remitting multiple sclerosis: Plegridy, a PegInterferon beta-1a, approved in European Union

The European Commission ( EC ) has granted marketing authorization for Plegridy ( Peginterferon beta-1a ) as a treatment for adults with relapsing-remitting multiple sclerosis ( RRMS ), the most common form of multiple sclerosis. Plegridy is dosed … more

Multiple sclerosis: Gilenya reduced relapse rates, new MRI lesion counts, brain volume loss and disability progression in previously-treated patients with high disease activity

New analyses of pooled data from the FREEDOMS and FREEDOMS II trials have shown the consistent efficacy of Gilenya ( Fingolimod ) on four key measures of multiple sclerosis disease activity – reducing relapses, new MRI lesion counts, brain volume … more

Atacicept increases clinical disease activity in relapsing multiple sclerosis

Depletion of B lymphocytes is associated with suppression of inflammatory activity in multiple sclerosis. A study has assessed the safety and efficacy of Atacicept, a recombinant fusion protein that suppresses B-cell function and antibody … more

Current perspectives on chronic cerebrospinal venous insufficiency

Chronic cerebrospinal venous insufficiency ( CCSVI ) was initially defined as a clinical syndrome comprising stenoses of the internal jugular and/or azygos veins, characterized by collateral venous outflows and reduced cerebral blood flow, and was … more