Medical Updates
Updates in Internal Medicine
Advances and updates in Internal Medicine by Xagena – Xagena Medical News
Hypertension: efficacy and safety of Valsartan and Nebivolol as fixed-dose combination
The fixed-dose combination of any two antihypertensive drugs from different drug classes is typically more effective in reducing blood pressure than a dose increase of component monotherapy. Researc …
Melanoma treated with the anti-PD-1 monoclonal antibody Pembrolizumab: clinical efficacy and correlation with tumor PD-L1 expression
Pembrolizumab ( MK-3475 ) has demonstrated antitumor activity and acceptable safety in a phase I melanoma cohort. Researchers have provided updated efficacy data and correlation with tumor PD-L1 exp …
FDA: no clear evidence of increased cardiovascular risks associated with use of the blood pressure medication Olmesartan in patients with diabetes
The FDA ( Food and Drug Administration ) has completed its safety review and has found no clear evidence of increased cardiovascular risks associated with use of the blood pressure medication Olmesart …
Pooled analysis of LUX-Lung 3 and LUX-Lung 6 comparing Afatinib with chemotherapy: overall survival in patients with advanced non-small cell lung cancer harboring common EGFR mutations
Afatinib ( Giotrif ) is an oral, irreversible ErbB family blocker of EGFR, HER2, ErbB3 and ErbB4 signalling. LUX-Lung 3 ( LL3 ) has compared Afatinib with Cisplatin / Pemetrexed in 345 patients recrui …