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Medical Updates

Updates in Internal Medicine

Advances and updates in Internal Medicine by Xagena – Xagena Medical News

Hypertension: efficacy and safety of Valsartan and Nebivolol as fixed-dose combination

The fixed-dose combination of any two antihypertensive drugs from different drug classes is typically more effective in reducing blood pressure than a dose increase of component monotherapy. Researc …

Melanoma treated with the anti-PD-1 monoclonal antibody Pembrolizumab: clinical efficacy and correlation with tumor PD-L1 expression

Pembrolizumab ( MK-3475 ) has demonstrated antitumor activity and acceptable safety in a phase I melanoma cohort. Researchers have provided updated efficacy data and correlation with tumor PD-L1 exp …

FDA: no clear evidence of increased cardiovascular risks associated with use of the blood pressure medication Olmesartan in patients with diabetes

The FDA ( Food and Drug Administration ) has completed its safety review and has found no clear evidence of increased cardiovascular risks associated with use of the blood pressure medication Olmesart …

Pooled analysis of LUX-Lung 3 and LUX-Lung 6 comparing Afatinib with chemotherapy: overall survival in patients with advanced non-small cell lung cancer harboring common EGFR mutations

Afatinib ( Giotrif ) is an oral, irreversible ErbB family blocker of EGFR, HER2, ErbB3 and ErbB4 signalling. LUX-Lung 3 ( LL3 ) has compared Afatinib with Cisplatin / Pemetrexed in 345 patients recrui …